Ki-1 antigen was found by a monoclonal antibody, made against a Hodgkin' disease-derived cell line (L428) that reacted with Redd-Sternberg cells in Hodgkin's disease and a few lymphocytes around lymphoid follicle. In 1985, Stein et al identified
a
large
cell anaplastic lymphoma showing a distinctive pleomorphic appearance, sinus growth pattern, and reactivity to Ki-1.
We report a case of Ki-1 positive large cell anaplastic lymphoma, which was presenting as a elevated plaque on the skin of popliteal fossa in a 69-year-old female.
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